The work is devoted to the scientific problem of improving the complex approach to the urbanized territories management in order to increase the ecological safety under pandemic threats. Construction trends have always showed the ability to evolve after the crisis, and in the context of the COVID-19 pandemic, densely populated cities were the most vulnerable to the risk of infection. Improving the ecological safety of the urbanized environment requires new urban space strategies, increasing spatial functionality, decentralization of megacities together with raising the potential of micromobility. The method of calculating the indicators of ecological safety of Kyiv districts has been formalized: Darnytskyi (20,984), Holosiivskyi (20,646), Dniprovskyi (19,417), Shevchenkivskyi (16,649), Desnyanskyi (16,275), Solomyanskyi (14,743), Obolonskyi (12,560), Sviatoshynskyi (11,916), Podilskyi (5,420), Pecherskyi (1,758), which creates the basis for scientific methods of comprehensive assessment and optimal forms of environmental safety management of urbanized areas on the example of Kyiv. The primary patterns of the spread of pandemic threats have been established in the districts of Kyiv, where the intensity of COVID19 infection has an experessed territorial nature. The correspondence between the number of infected people and the total number of kindergartens, schools, colleges, and higher educational institutions in the districts has been established, which makes it possible to make appropriate adjustments in the development of stabilization measures and create conditions for reliable safety of human life, taking into account critical situations. It is proposed to improve the Development Strategy of Kyiv using advanced innovative technologies for green construction for such sectors of urban development as city development, land relations, housing, and communal services, transport and urban mobility, public space, energy-saving, resource management, and waste management, security environment and ecopolitics, decentralization of areas, increasing spatial functionality, increasing green areas, increasing the potential for micromobility, spreading energy-efficient technologies and efficient use of resources, calculating the entire life cycle of materials, recycling waste and proper disposal of their hazardous component, increasing the level of environmental safety to preserve public health in the face of pandemic threats